Oncogenes and inflammasomes in lupus nephritis
نویسندگان
چکیده
منابع مشابه
The prognosis of lupus nephritis in children
Introduction: Lupus nephritis is a systemic disease which affects different organs. The present study was designed to review lupus nephritis, in children its outcome and the related factors. Methods: We reviewed 48 children with lupus nephritis. Clinical and epidemiological features were studied. The patients’ outcomes and related factors were analyzed. Patient and renal survival rate were ca...
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Lupus nephritis is a common solid organ manifestation of systemic lupus erythematosus (SLE). The disease is tightly linked to the production of autoantibodies and circulating immune complexes, i.e. immune complex glomerulonephritis. In this process chemokines mediate multiple biological effects, e.g. orchestrating proinflammatory microenvironments, the recruitment of immune cell subsets into th...
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OBJECTIVE To determine the clinicopathological pattern of lupus nephritis in paediatric nephrology patients. DESIGN Case series study. PLACE AND DURATION OF STUDY The department of paediatric nephrology at the Children's Hospital and Institute of Child Health, Lahore, Pakistan, over a period of five years from January 2001 to December 2005. PATIENTS AND METHODS Twenty six patients upto th...
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متن کاملComplement in Lupus Nephritis
The complement cascade consists of a series of plasma proteins that not only play a vital role in destroying pathogens but also mediate humoral and cellular interactions within the immune system (Figure). Recent work, driven particularly by the availability of gene-targeted mice, has considerably increased our understanding of the links between the complement system and glomerular disease. In t...
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ژورنال
عنوان ژورنال: Nature Reviews Rheumatology
سال: 2019
ISSN: 1759-4790,1759-4804
DOI: 10.1038/s41584-019-0194-x